Spermatogenesis in Explanted Fetal Mouse Testis Tissues
نویسندگان
چکیده
منابع مشابه
In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues
Research on in vitro spermatogenesis is important for elucidating the spermatogenic mechanism. We previously developed an organ culture method which can support spermatogenesis from spermatogonial stem cells up to sperm formation using immature mouse testis tissues. In this study, we examined whether it is also applicable to mature testis tissues of adult mice. We used two lines of transgenic m...
متن کاملCryopreservation of testis tissues and in vitro spermatogenesis
Cancer treatments, either chemo- or radiotherapy, may cause severe damage to gonads which could lead to the infertility of patients. In post-pubertal male patients, semen cryopreservation is recommended to preserve the potential to have their own biological children in the future; however, it is not applicable to prepubertals. The preservation of testis tissue which contains spermatogonial stem...
متن کاملMesonephric contribution to testis differentiation in the fetal mouse.
Testes from 11.5-day-old mouse embryos, with and without attached mesonephroi, were cultured for 7 days. Isolated testes failed to develop well-differentiated testis cords: however, when cultured attached to a mesonephros from either a male or a female donor embryo, testes developed cords that were normal in appearance. Testes cultured next to a mesonephric region but separated from it by a per...
متن کاملThe Effect of Pentoxiphylin on Histological Changes of Testis and Spermatogenesis Indexes in Mouse Treated With Dexamethasone
Background and Objectives: Dexamethasone is one of the common drugs, which is used in the human severe allergies and can cause defect in the reproductive system by inducing oxidative stress. In this study, the effect of pentoxifylline as a potent antioxidant, was investigated on changes in testicular tissue and spermatogenesis indices in mice treated with dexamethasone. Methods: In this expe...
متن کاملMAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice
The transcription factor MAFB is an important regulator of the development and differentiation of various organs and tissues. Previous studies have shown that MAFB is expressed in embryonic and adult mouse testes and is expected to act as the downstream target of retinoic acid (RA) to initiate spermatogenesis. However, its exact localization and function remain unclear. Here, we localized MAFB ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2016
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.116.140277